Evaluation of Diffusivity Values and Extraction Speed Constants on Black Pepper Piperine Isolation

Mega Mustikaningrum, Desty Arista, Retno Dwi Nyamiati, Dodi Eko Nanda

Abstract


Piperine is a type of bioactive compound that can be isolated from black pepper. Currently the utilization of piperine is dominated by the health sector. In this study, piperine was isolated using the Soxhlet method. The purpose of this research is to propose a mathematical model to determine the value of the diffusivity (DA) of piperine, the extraction rate constant (k) and the piperine isolation equilibrium constant for commercial designs. Based on the results obtained the value of DA was obtained at 0.1878 m2/minute, the value of k was obtained at 0.0012 m/minute and the value of K was obtained at 0.900. Extraction was carried out using 96% ethanol solvent with a ratio of 25:1 to black pepper samples using the soxhletation method of 5 circulations. The resulting piperine extract was 55.46 mol/liter

Keywords


Black pepper; piperine; diffusivity ; soxhlet ; extraction speed constant

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References


T. Thangselvabal, C. G. L. Justin and M. Leelamathi, "Black Pepper (Piper Nigrum L.) "The King Of Spices'- A Review," Agricutural Reviews, pp. 89-98, 2008.

K. Vasavirama and M. Upender, "Piperine : A Valuable Alkaloid From Piper Species," International Journal of Pharmacy and Pharmaceutical Science, pp. 34-38, 2014.

C. D. Doucette, G. Rodgers, R. S. Liwski and D. W. Hoskin, "Piperine from black pepper inhibits activation-induced proliferation and effector function of T lymphocytes," Journal of Cellular Biochemistry, pp. 2577-2588, 2015.

A. Tiwari, K. R. Mahadik and S. Y. Gabhe, "Piperine: A comprehensive review of methods of isolation, purification, and biological properties," Medicine in Drug Discovery , p. 100027, 2020.

C. R. Quijia and M. Chorili, "Characteristics, Biological Properties and Analytical Methods of Piperine: A Review," Critical Reviews in Analytical Chemistry, pp. 62-77, 2019.

I.-U. Haq, M. Imran, M. Nadeem, T. Tufail, T. A. Gondal and M. S. Mubarak, "Piperine: A review of its biological effects," Phytotherapy Research , pp. 680-700, 2020.

Y. Liu, J. B. Friesen, J. B. McAlpine, D. C. Lankin, S.-N. Chen and G. F. Pauli, "Natural Deep Eutectic Solvents: Properties, Applications, and Perspectives," Journal of Natural Product , pp. 679-690, 2018.

M. H. Zainal-Abidin, M. Hayyan, A. Hayyan and N. S. Jayakumar, "New horizons in the extraction of bioactive compounds using deep eutectic solvents: A review," Analytica Chimica Acta, pp. 1-23, 2017.

R. Subramanian, P. Subbramaniyan, J. N. Ameen and V. Raj, "Double bypasses soxhlet apparatus for extraction of piperine from Piper nigrum," Arabian Journal of Chemistry, pp. S537-S540, 2016.

P.D.Hamrapurkar, K. Jadhav and S. Zine, "Quantitative Estimation of Piperine in Piper nigrum and Piper longum Using High Performance Thin Layer Chromatography," Journal of Applied Pharmaceutical Science, pp. 117-120, 2011.

S. Bachtler and H.-J. Bart, "Polyphenols from Red Vine Leaves Using Alternative Processing Techniques," Processes, p. 262, 2018.

A. L. B. Dias, C. S. A. Sergio, P. Santos, G. F. Barbero, C. A. Rezende and J. Martínez, "Ultrasound-assisted extraction of bioactive compounds from dedo de moça pepper (Capsicum baccatum L.): Effects on the vegetable matrix and mathematical modeling," Journal of Food Engineering, pp. 36-44, 2017.

M. Kuhn, S. Lang, F. Bezold, M. Minceva and H. Briesen, "Time-resolved extraction of caffeine and trigonelline from finely-ground espresso coffee with varying particle sizes and tamping pressures," Journal of Food Engineering, pp. 37-47, 2017.

V. Sant’Anna, A. Brandelli, L. D. F. Marczak and I. C. Tessaro, "Kinetic modeling of total polyphenol extraction from grape marc and characterization of the extracts," Separation and Purification Technology, pp. 82-87, 2012.

J. Pinela, M. Prieto, A. M. Carvalho, M. F. Barreiro, M. B. P. Oliveira, L. Barros and I. C. Ferreira, "Microwave-assisted extraction of phenolic acids and flavonoids and production of antioxidant ingredients from tomato: A nutraceutical-oriented optimization study," Separation and Purification Technology, pp. 114-124, 2016.

D. Beverly, E. Lopez-Quiroga, R. Farr, J. Melrose, S. Henson, S. Bakalis and P. J. Fryer, "Modelling mass and heat transfer in multiphase coffee aroma extraction," Industrial & Engineering Research, pp. 11099-111112, 2020.

B. Corrochano, J. Melrose, A. Bentley, P. Fryer and S. Bakalis, "A new methodology to estimate the steady-state permeability of roast and ground coffee in packed beds," Journal of Food Engineering, pp. 106-116, 2015.

M. Romdhane and d. C. Tizaoui, "The kinetic modelling of a steam distillation unit for the extraction of aniseed (Pimpinella anisum) essential oil," Journal of Chemical Technology and Biotechnology, pp. 759-766, 2005.

H. A. Harouna-Oumarou, H. Fauduet, C. Porte and Y.-S. Ho, "Comparison of Kinetic Models for the Aqueous Solid–Liquid Extraction of Tilia Sapwood in a Continuous Stirred Tank Reactor," Chemical Engineering Communications, pp. 537-552, 2007.




DOI: https://doi.org/10.31315/e.v20i2.8996

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